Tions of APS. Norethisterone is normally safe to take, but it > 자유게시판

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Tions of APS. Norethisterone is normally safe to take, but it is not suitable for patients with an increased risk of DVT. Also, the simultaneous management of thrombosis and heavy vaginal bleeding is a challenge for clinicians since there are no evidence-based guidelines regarding the management of these patients. Consent Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.Abbreviations APS: Antiphospholipid syndrome; IVC: 1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Inferior vena cava; aPL: (R)-1-(3-Chlorophenyl)ethan-1-ol Antiphospholipid; VTE: Venous thromboembolism; DVTs: Deep vein thrombosis; PR: Pulse rate; BP: Blood pressure; RR: Respiratory rate; WBC: White Blood Cells; Hb: Hemoglobin; MCV: Mean Corpuscular Volume; MCH: Mean Corpuscular Hemoglobin; PT: Prothrombin Time; INR: International Normalized Ratio; PTT: Partial Thromboplastin Time; APC: Activated protein C; AST: Aspartate Aminotransferase Test; ALT: Alanine Aminotransferase Test; ALP: Alkaline Phosphatase; TP: Total Protein; ALB: Albumin; T.BILI: Total Bilirubin; D.BILI: Direct Bilirubin; LDH: Lactate Dehydrogenase; HCQ: Hydroxychloroquine. Competing interests The authors declare that they have no competing interests. Authors' contributions SAA was the patient's primary physician during the course of treatment described above, and was responsible for the literature review, formulation, editing and submission of the manuscript. MWE and MEE were responsible for the critique of the hematology and radiology components of the manuscript respectively. All authors read and approved the final manuscript. Acknowledgements The authors would like to thank Dr Hassan Ali Alfaraj, the medical specialist in the unit during 2011, for conducting the follow-up visits journal.pone.0167038 with the patient. Author details 1 Department of Rheumatology, Dammam Medical Complex, Dammam, Saudi Arabia. 2Department of Hematology, Dammam Medical Complex, Dammam, Saudi Arabia. 3Department of Radiology, Dammam Medical Complex, Dammam, Saudi Arabia. Received: 18 October 2014 Accepted: 20 February5.6.7.8.9.10.11.12.13.14.15. 16.ischemic strokes as initial presentation of systemic lupus erythematosus. J Pediatr Hematol Oncol. 2005;27:527?0. Ramon I, Mathian A, Bachelot A, Hervier B, Haroche J, Boutin-Le ThiHuoung D, et al. Primary adrenal insufficiency due to bilateral adrenal hemorrhageadrenal infraction in the antiphospholipid syndrome: long term outcome of 16 patients. J Clin Endocrinol Metabol. 2013;98:3179?9. PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/13485127 Ruiz-Irastorza G, Khamashta MA, Hunt BJ, Escudero A, Caudrado MJ, Hughes GR. Bleeding and recurrent thrombosis in definite antiphospholipid syndrome: analysis of a series of 66 patients treated with oral anticoagulation to a target international normalized ratio of 3.5. Arch Intern Med. 2002;162:1164?. Vieregge GB, Harrington TJ, Andrews DM, Carpintero MF, Green DF, Nayer A. Catastrophic antiphospholipid syndrome with severe acute thrombotic microangiopathy and hemorrhagic complications. Case Rep Med. 2013;2013:915309. Park IC, Baek YH, Han SY, Lee SW, Chung WT, Lee SW, et al. Simultaneous intrahepatic and subgaleal hemorrhage in PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/22763976 antiphospholipid syndrome following anticoagulation therapy. World J Gastroenterol. 2013;19:6494?. Ramya T, Prakash B, Devi B. Norethisterone induced cerebral venous sinus thrombosis (CVST): a rate case report and review of literature. Int J Reprod Contracept Obstet Gynecol. 2014;3:231?. National Health Service.